Annihilator could refer to several things:
- Annihilator, a Super Star Destroyer under the command of Grand General Cassio Tagge
- DT-57 "Annihilator" blaster
- Annihilator, an alias used by the droid Bollux.
- Annihilator, Admiral Gaarn's Executor-class Star Dreadnought.
- Annihilator, a Star Destroyer which patrolled near Hutt Space and the Periphery.
- Annihilator, an Imperial command ship.
- Annihilator 1, Beri Tulon's personal All Terrain Armored Transport.
- Annihilator, a nonexistent superweapon.
- Annihilator-class starfighter manufactured by the One Sith.
- Scorpenek annihilator droid, built by the Colicoid Creation Nest.
- DT-57 heavy blaster pistol also known as the "Annihilator".
- Hypermatter annihilator reactor, used in the Death Stars.
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