The Blue Shadow Virus was a deadly disease that spread like a plague in the galaxy many years before the Clone Wars. Although the virus was eradicated, Doctor Nuvo Vindi of the Confederacy of Independent Systems re-engineered the virus on Naboo. He attempted to spread it across the planet, but he was stopped by the Galactic Republic and the Jedi Order.
- "The Blue Shadow Virus in its natural form thrives only in water."
- ―Dr. Nuvo Vindi
The Blue Shadow Virus, in its natural form, was a waterborne virus. A victim infected with the plague only had 48 hours to live before the virus became fatal. It was notorious for being supposedly incurable, though an antidote was able to be synthesized with reeksa root, a rare plant only found on the planet Iego.
- "Your eyes do not deceive you. I have perfected an airborne strain of the Blue Shadow Virus."
- ―Dr. Nuvo Vindi
Several thousand years before the Clone Wars, the Blue Shadow Virus encompassed the galaxy, killing millions who drank the infected water. The virus was eventually eradicated, only to be reintroduced by Doctor Nuvo Vindi during the Clone Wars. Vindi created several bombs that held an airborne version of the virus, which he planned to release on several key systems that were involved in creating galaxy-wide war. Though the release of Vindi's bombs across the galaxy was stopped by the Jedi, some of the virus was released inside of Vindi's laboratory on the planet Naboo. This small amount of virus infected senator Padmé Amidala, Jedi Padawan Ahsoka Tano, as well as several Clone troopers, but fortunately never left the confines of the lab. Two Jedi, Obi-Wan Kenobi and Anakin Skywalker, eventually discovered a way to make an antidote to the virus from the reeksa root, which they found on the planet Iego. After the Jedi obtained the root from Iego, an antidote was created and all that were infected were cured.
- Star Wars: The Clone Wars – "Blue Shadow Virus" (First appearance)
- Star Wars: The Clone Wars – "Mystery of a Thousand Moons"
- Star Wars: Absolutely Everything You Need to Know
- Star Wars: Galactic Atlas
- ; image #14 (of 29)
- ; image #19 (of 29)