The Calipsa Run was a minor hyperspace route located in the Tapani sector, that because of very few debris in the area made travel on this route very fast. The route connected the Calipsa Province and the Mecetti Province with the Procopian Shipping Lane at Estaph. Some of the notable worlds on this route were Calipsa, New Javis, Lorenz, Grella and Nella.

The Calipsa Run was neglected by many bulk cargo shippers until House Cadriaan issued stiff tariffs against House Calipsa.