D'yra Calisse was a female Twi'lek, who lived during the waning years of the Galactic Republic.


D'yra Calisse worked for Hedrett Shipping and Investments as the co-pilot of the Fricasseed Nerf, a YT-1300 light freighter. During the Clone Wars, she was aboard the ship when it collided with a comet fragment in the Cularin system and was left drifting in space. However, she and the rest of the crew of the Nerf were rescued by the Heroes of Cularin.