The Shapani Run was a hyperroute in the Tapani sector. It originated in Pelagia Province and was the fastest route to Cadriaan space that contained the Shapani Bypass, a spur of the longer Rimma Trade Route.

Following the Mecetti Purge Pelagia ensured that its enemies, including House Calipsa, paid high tariffs for passing through. At one time Calipsa was banned from Pelagian space and therefore isolated from the Shapani Run.