Spirit ichor was the base for all magic employed by the Nightsisters of Dathomir during the Clone Wars. According to Mother Talzin, it came from channeling the Winged Goddess and was manifested as green smoke.
Spirit ichor could be manipulated in a large variety of ways by a shaman. A shaman could manipulate spirit ichor into physical objects such as a goblet of blackroot, as Mother Talzin did for Count Dooku when he visited Dathomir during the Clone Wars. Mother Talzin was also seen later to conjure a Lightsaber in order to combat Jedi Master Mace Windu. Spirit ichor could also be used for divination; for mesmerism, to induce a victim into a trancelike state; for totem magic; or to conjure the Water of Life for healing purposes and other uses.
As Mother Talzin did for Asajj Ventress, Naa'leth, and Karis, spirit ichor could be manipulated to produce a mist that allowed assassins to operate "midway" between the physical and spirit realms, cloaking them with near-invisibility. Savage Opress was also transformed into an avatar of primal anger by Talzin and a coven of spellcasters via spirit ichor.
- Darth Plagueis (Mentioned only) (As "ichor")
- Restraint (Mentioned only)
- Star Wars: The Clone Wars – "Nightsisters" (First appearance)
- Star Wars: The Clone Wars – "Monster"
- Star Wars: The Clone Wars – "Witches of the Mist"
- Star Wars: The Clone Wars – "Massacre"
- Star Wars: The Clone Wars – "Revenge"
- Star Wars: The Clone Wars – "The Disappeared Part II"
- Star Wars: Ewoks - Shadows of Endor
- Book of Sith: Secrets from the Dark Side (First identified as Spirit ichor)